Aug 03

Illicit Uses of Buprenorphine (Suboxone, Buprenex, Subutex)

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Illegal uses of Buprenorphine (Suboxone, Buprenex, Subutex) based on DEA Study

Like other opioids commonly abused, buprenorphine is capable of producing significant euphoria. Data from other countries indicate that buprenorphine has been abused by various routes of administration (sublingual, intranasal and injection) and has gained popularity as a heroin substitute and as a primary drug of abuse.

Large percentages of the drug abusing population areas consist of:

  • France
  • Ireland,
  • Scotland
  • India
  • Nepa
  • Bangladesh
  • Pakistan
  • New Zealand

These cities have reported abusing buprenorphine by injection and in combination with a benzodiazepine.

Sources of Buprenorphine Illicit Uses Information

  • The National Forensic Laboratory Information System (NFLIS) is a DEA database that collects scientifically verified data on drug items and cases submitted to and analyzed by state and local forensic laboratories.
  • The System to Retrieve Information from Drug Evidence (STRIDE) provides information on drug seizures reported to and analyzed by DEA laboratories. In 2010, federal, state and local laboratories identified 7,786 exhibits as buprenorphine; five times the number of buprenorphine exhibits (1,291) identified in 2006.
  • Drug Abuse Warning Network (New DAWN ED), an estimated 14,266 emergency room visits were associated with buprenorphine misuse in 2009, more than three times the 4,440 estimated number of buprenorphine visits in 2006.

User Population of Buprenorphine

In countries where buprenorphine has gained popularity as a drug of abuse, it is sought by a wide variety of narcotic abusers: young naϊve individuals, non-addicted opioid abusers, heroin addicts and buprenorphine treatment clients.

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Jul 21

Taper 101 for Addictive Opioids like Buprenorphine Naloxone

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Tapering 101 – Addictive Pain Killers and Opiates

  • Heroin
  • Demerol
  • Methadone
  • Morphine
  • Hydrocodone
  • Oxycodone
  • Suoxone
  • Dilaudid
  • Vicodin
  • Percocet

 

 Suboxone Taper

Factors that affect the Taper From Addictive Opiates (Opiate, Methadone, Morphine, Hydrocodone, Oxycodone, Suoxone and Dilaudid)

  • how long you’ve been on the med
  • what dose you’re on
  • your age
  • what other meds you’re taking
  • your general health.

 

Opiate Tapering using Gradual Dose Reduction (aka Tapering)

The purpose of tapering a medication is to find an optimal dose or to determine whether continued use of the medication is needed.  A taper of an addictive opiate such as (Opiate, Methadone, Morphine, Hydrocodone, Oxycodone, Suboxone, and Dilaudid) may be made much more comfortable using tapering.  You can use the Buprenorphine Naloxone & Suboxone Tapering Tool on this site to plan your own personal taper.

Buprenorphine Taper

The Buprenorphine Naloxone & Suboxone Tapering Tool

Cold Turkey – Stopping Suboxone or Opioid Medications

What to do if your doctor says you can stop pain killers cold-turkey?

Question: I’ve been on Suboxone. My doctor has now said I can stop taking the medication. I’ve heard from others that you should not stop taking this medication cold turkey but should wean from

it using a gradual reduction in dose over time. The doctor said I should be fine that 4mg daily is not that much to stop. Should I just stop or taper on my own?
—Carlos, Sanford, Florida
ANSWER: Opioid medicines have common and easily seen withdrawal symptoms and some have rebound effects. Overall, pain killers can be tapered without problem but when your physician says you can stop them, most likely, you don’t need to worry about tapering off. (Ask questions if you’re not sure.)

Some other medications, such as antidepressants and blood-pressure meds, do need a tapering schedule. Sometimes docs will taper them over a short timeframe like 2 weeks or sometimes over a long period such as a year.  It depends on how long you’ve been taking them and what dose.

 

What can happen if you stop taking certain opioids (pain-killers) cold-turkey?

For opioids such as (Opiate, Methadone, Morphine, Hydrocodone, Oxycodone, Suoxone and Dilaudid):

  • high blood pressure
  • rapid heart rate
  • seizures
  • anxiety

 

When stopping medications, a taking your time may save your life, health and minimize withdrawal symptoms.
A really nice drug tapering tool that can be used for just about any medication including opioids (Opiate, Methadone, Morphine, Hydrocodone, Oxycodone, Suoxone and Dilaudid)
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Jun 26

Opioid Withdrawal – War Stories (Oxycodone, Hydrocodone, Morphine, Heroin, Suboxone)

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My Opioid War Story

 

Something is wrong… something is damn wrong… fix it now

If you have been addicted to any opioid then you are well aware that quitting an opioid is much more difficult than anyone else knows.  They refer to the time they quit smoking, or they time they stopped drinking soda and think that quitting opioids is some decision that you can just make and do it.

I would never wish the pain of withdrawal on any of my friends, but I can’t deny there have been times I wish that they could experience the feeling of being without opioids for just one hour and then let them tell me how easy it will be.

We have suffered through the many sleepless nights where our our body spasms unexpectedly like some sort of a seizure.  Some people say their arm twitches, some people experience severe restless legs but everyone experiences some soft of visible twitching body movement where your brain is telling your body that something is wrong, something is damn wrong, fix it now!   We are the ones that can share war stories about quitting opioids and the withdrawal that kept is in the bed (or hospital) for a week, and we’d watch the clock for what felt like eternity.  The opioid withdrawal made minutes feel like hours, and hours like days.

The worst withdrawal symptoms for me:

  • Pain – full body pain
  • Severe Anxiety and Restlessness
  • Nausea and Vomiting, Gut wrenching feeling
  • Cold and Hot spells
  • Inability to sleep
  • More pain and leg kicking
  • GI Joe Squirts (late stages of withdrawal)
  • Runny Nose (early stages of withdrawal)

 

What physical thing do you remember while suffering through opioid withdrawal?

My opioid withdrawal happened several years ago and other than the feelings that I felt there is one thing I have a very detailed image of in my mind.  The clock that was hanging near the bed I was laying in as I suffered through opioid withdrawal.  I can remember every detail about the clock on the wall as I suffer through days of opioid withdrawal.  The big round clock made of plastic and colored like aged brass.  It had a tan background and roman numerals and the hour hand had a strange pointer almost like the devils pitchfork.

Quitting Suboxone - The Clock

I have visions of that clock burned into my mind at various time through out the day and when the hour hand had moved from four to six I recall wondering if I was going to make it and if the opioid withdrawal would ever end.  The pain did end, and going through the pain was worth it, but the pain never ends for an addict in my mind.  There is a different pain once you are sober called boredom but that is for another day.

So let me know about your war story.

 

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Jun 24

Trick to Quitting Suboxone (buprenorphine & naloxone) or other Opioids

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The Trick to Quitting  Buprenorphine Naloxone with Minimial Withdrawal Symptoms

 

Withdrawal from Buprenorphine Naloxone or other Opioids

Quitting opioids really sucks, for lack of better words.  I’ll never forget the many sleepless nights spent kicking my legs because they hurt so bad.  I’ll never forget the opioid withdrawal symptoms where my body would change from hot to cold in a flash, literally.  One minute I’d have ten blankets on and be shivering and the next I’d be sweating profusely.  And the clock watching I’ve mentioned in other articles… that is something I’ll remember to the day I die as minutes went by they felt like hours.  I’ve got another article called war stories of quitting opioids where I describe my “war story” in more detail.

 

The Trick to Quitting  Buprenorphine Naloxone  (Suboxone)

As I promised, there really is a way to quit  Buprenorphine Naloxone (Suboxone) that involves very little withdrawal pain, and I suspect you can handle some pretty intense withdrawal pain if you are here unless you had an unlimited supply of money and drugs and somehow remained alive.  I used the word “TRICK” on purpose because in a way this is some sort of trick or decption that we play on our mind.

 

(deception n)     (d-spshn)

1. the act of deceiving or the state of being deceived
2. something that deceives; trick

[Middle English decepcioun, from Old French deception, from Late Latin dcepti, dceptin-, from Latin dceptus, past participle of dcipereto deceive; see deceive.]

The American Heritage® Dictionary of the English Language, Fourth Edition copyright ©2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.

 

Yes you are going to deceive your body, play a trick on it by weaning it off of opioids  to taper off of the drug so slowly that your body doesn’t notice it.

Image of a child pacifier - Weaning Off Buprenorphine Naloxone (Suboxone)

The Pacifier

This may sound crazy but it really works, it reminds me of a similar method of deception that I played on my daughter when she was a child.  As a parent we used a pacifier to keep our daughter satisfied when we were too busy to do it ourselves, it sounds evil but it is quite common and not really mean at all. If you don’t know what a pacifier is… well a plastic rubbery sucking thing that a baby sucks on to “pacify” themselves and deceives them into thinking they are sucking on a bottle of milk or the mothers breast.

 

, The baby becomes emotionally attached to them especially if you use them too often, and when the baby starts to grow older it can become a challenge to make the baby stop using the pacifier without driving you crazy by crying too much.

So, I got creative and decided to try something other than cold-turkey and just taking the pacifier away.  I took out the scissors and cut a very small portion of the tip off of the pacifier and gave it to my daughter… as I expected she took to it like an addict would take to a couple crushed Oxycodone 30 and a straw.  Bingo! I thought this just might work, but the key was going slow I made the mistake of cutting off too much a few days later and my daughter made a funny face, spit out the pacifier and started crying.

 

So each day, I would cut a sliver of the pacifier off and there would be no problems.  As the days went on the pacifier would start to fall out of my daughters mouth but it was gradual so she got used to picking it back up and putting it in her mouth, or she would hold it with her hand.  This is the way to quit Suboxone or any other addictive substance, by tricking your body very slowly and gradually.  Several weeks had gone by and the pacifier was cut so small that my daughter had to hold it to keep it in her mouth and we found that she didn’t cry for it very much at all.  Eventually she stopped using it because it wasn’t worth the effort of holding that nub of a pacifier in her mouth!

The Tapering Plan – Plotting your Taper from Buprenorphine Naloxone

The tapering strategy will work for any opioid, from Oxycodone and Hydrocodone to Morphine, Methadone, Heroin & Hydromorphone.  The reason you don’t hear of many success stories of persons tapering from Oxycodone is because it has too short of a half-life, meaning that the time it takes for the drug to be eliminated from your blood stream is short.  Buprenorphine Naloxone is an extremely long lasting opioid with a mean half-life of 37 hours.  The speed at which you taper is different for everyone.

Tapering off of any drug should always be planned and completed under supervision of a doctor.  I will be writing about this subject soon, and will go into detail about the actual tapering plan.  You can use my Suboxone Taper Charting tool to plot a taper plan off of any drug!

 

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Jun 17

Experiences, Facts and Stories about Suboxone Withdrawal

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How long does Suboxone Withdrawal Last?

This is the number one question asked and in simple terms– it lasts a pretty long time and it sucks really bad.

Now for some real medical explanation about the length of Suboxone Withdrawal.  First of all, Buprenorphine’s duration of action is not dependent on the serum halflife.  It is highly protein bound a actnd primarily hepatically metabolized (CYP 3A4). The agent is subject to extensive first pass metabolism. Buprenorphine undergoes Ndealkylation to norbuprenorphine and glucoronidation. Norbuprenorphine is an active metabolite, which has little efficacy but is a potent respiratory depressant.

Suboxone StripsSo what does this mean?  It means that Suboxone undergoes changes as your liver metabolizes is, and each resultant metabolite has specific actions and lengths of duration.  The long half-life of Suboxone is a good and bad thing, it is good because the Suboxone takes a long time to be filtered from your body.  But the long half-life can make withdrawals very long, and from personal experience I can say that it is relatively severe, not as severe as withdrawal from oxycontin or heroin, but annoyingly long lasting.  The other negative of the way Suboxone is metabolized is that it turns into different substances that themselves have a duration of action and can contribute to withdrawal symptoms.

From experience, and talking with others I have learned that the best way to minimize withdrawal symptoms is a very, very slow and very very gradual taper.  You can use the Suboxone Taper Charting Tool on this site to build your own taper schedule and see if your doctor is willing to let you follow it. You should never adjust your medication without doctor approval.

Drug Abuse and Dependence:

Buprenorphine can cause physical dependence with continuous administration. Individuals may experience withdrawal symptoms upon
abrupt discontinuation. However, the effects are usually milder than what is experienced with a full opioid agonist.

Adverse Effects:

Side effects of buprenorphine are similar to those of other opioids.

Common:

  • nausea
  • vomiting
  • constipation
  • headaches
  • sweating
  • sleep difficulties
  • hypotension
  • sedation
  • flu-like symptoms.

Buprenorphine can precipitate an opioid withdrawal syndrome.

Signs and symptoms of opioid withdrawal include:

  • dysphoric mood
  • GI distress (nausea, vomiting, diarrhea)
  • myalgias
  • lacrimation
  • rhinorrhea
  • pupillary dilation
  • sweating
  • piloerection
  • yawning
  • mild fever
  • insomnia.

Rare:

  • Respiratory depression, which can potentially result in death.
  • Most of the fatal cases occurred in combination with other CNS depressants such as alcohol or benzodiazepines.

Stories about Suboxone Withdrawal – One I respectfully disagree with

I found this story on answers.com about a persons experience with Suboxone Withdrawal and it is quite a bit different than I’ve experience and close friends of mine have experienced.  I have found that Suboxone withdrawal last much longer although I do agree the symptoms are milder. YMMV. Also agree with the statement that cold-turkey Suboxone is bad. Long shallow taper is the way to go and I mean long and shallow.
Suboxone takes about 2-5 days for the worst part of the symptoms to go away, and a couple weeks for mild symptoms to deminish. It kinda sucks cuz I’m actually goin through it right now. Today is my third day and i decided to snort about .25 mg to take away the chills. Its not that bad though, I’ve definetly been through allot worse having been through withdrawls from herion, cocaine, and alchahol. Not all at once of course, I’ve taken each one to the limit many times in the past 4 years. Pretty crazy sein how I’m only 18 yrs. old. I swear i know almost everything about drugs. And trust me i know that’s not cool at all. I really hate drugs, they just seem to like me allot for some reason. but ya my fingers hurt so i hope i was a little bit of help. If you have any other questions about suboxone or ne thing else feel free to ask. Peace.
I have been on suboxone for 2 yrs and recently went off it. I quit it on a Monday, and didn’t notice anything for a few days, then the withdrawls kicked in. I was depressed, with diarreah, and cold and hot sweats and an overall feeling of pure exaustion. It’s been a little over a week now and I’m slowly feeling better each day. I still can’t stay asleep though. I thought the suboxone was a wonderful drug to get me off my lortab addiction, but they always told me there wouldn’t be any withdrawl with the suboxone. They lied.
IV,E COME OFF SUBUTEX COLD TURKEY THEN SUBOXONE YEARS LATER BY TAPERING.COLD TURKEY IS TERRIBLE AND IT TAKES 2 DAYS BEFORE YOU EVEN START TO W/D.THE WORST OF IT LASTS TIL ABOUT 10 TO 12 DAYS BUT YOU STILL CANT SLEEP RIGHT AND GET RESTLESS FOR AROUND SIX WEEKS AFTER QUITING.IF YOU TAPER ITS A LOT EASIER BUT YOU,VE GOT TO SLOW IT RIGHT RIGHT DOWN WHEN YOU GO UNDER 2MG.IF YOU TAKE YOUR TIME UNDER 2MG,AND ARE PREPARED TO DRAG IT OUT,THEN YOU WILL TAPER OFF IT A LOT EASIER.YES.YOU WILL STILL HAVE W/D SYMPTOMS BUT THEY WONT BE NEAR AS BAD AS GOING COLD TURKEY.BUPRENORPHINE W/D IS NOT AS BAD AS METHADONE W/D COLD TURKEY AS IV,E COME OFF THAT TOO.Read more: http://wiki.answers.com/Q/How_long_will_withdrawal_symptoms_from_suboxone_last#ixzz1y1cmBfqX
References:
1. Johnson, R.E., Strain, E.C., & Amass L. (2003). Buprenorphine: how to use it
right. Drug and Alcohol Dependence, 70, s59-s77.
2. Subutex®, Suboxone®. [package insert]. Reckitt-Benickser Pharmaceuticals.
Richmond, Va.
3. Johnson, R.E., Chutuape, M.A., Strain, E.C., Walsh, S.L., Stitzer, M.L., Bigelow, 
G.E. (2000). A comparison of levomethadyl acetate, burpenorphine, and
methadone for opioid dependence. NEJM, 343(18), 1290-1297.
4. Substance Abuse and Mental Health Services (SAMHSA). About Buprenorphine
Therapy. http://buprenorphine.samhsa.gov/about.html.
5. Johnson, R.E., Jaffe, J.H., Fudala, P.J. (1992). A controlled trial of burpenorphine
treatment for opioid dependence. JAMA, 267, 2750-2755.
6. Mattick RP, Kimber J, Breen C, Davoli M Buprenorphine maintenance versus
placebo or methadone maintenance for opioid dependence (Cochrane Review). In:
The Cochrane Library, Issue 4, 2003. Chichester, UK: John Wiley & Sons, Ltd.
7. Liu, Z.M., Cai, Z.J., Wang, X.P., Ge, Y., Li, C.M. (1997). Rapid detoxification of
heroin dependence by buprenorphine. Acta Pharmacologica Sinica, 18(2), 112-
114. 
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May 09

Suboxone Precipitated Withdrawal – Be Careful

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What is Suboxone Precipitated Withdrawal?

In short, precipitated withdrawal is a very quick and intense onset of opiate withdrawal symptoms.  It’s like quitting opiates but jumping from day one withdrawal to day four withdrawal, really bad.  It is relatively uncommon but bad enough that it should be avoided.  The precipitated withdrawal with Buprenorphine happens because of it’s high binding strength to opiate receptors, so basically the Buprenorphine pushes out the opiates in your brain and fills the opiate receptors with Buprenorphine (in Suboxone) so it’s almost like jumping from no withdrawal to day four withdrawal intensity– and can even be dangerous.  Buprenorphine is strong stuff– it beats the crap out of opiates and displaces the opiates from your opiate receptors taking you to hell in a hurry.

What happens if you get Suboxone Precipitated Withdrawal?

Well to be honest, if you are affected by precipitated withdrawal, you are going to feel rapid onset of opiate withdrawal symptoms, much faster than cold turkey, and no this will not reduce the “detox” time.  Common sense would say, take some opiates, the Suboxone isn’t working, but taking opiates once precipitated withdrawal has occurred would not be helpful because your receptors are blocked by the Buprenorpine which has a much stronger “hold” on the receptors than opiates rendering the opiates nearly useless.  The best advice I can give if this happens is go to the hospital and explain what happened, they can give you medicine to reverse the situation and make you feel better.

Avoiding Precipitated Withdrawal

You need to restrict intake of opiates for a period of time before taking Suboxone, basically you should be in some form of withdrawal.  If you are not in some pain you are risking precipitated withdrawals.  If you need to taper, use the taper charting tool on this site, you can plot your own taper charts.

Suboxone TaperAvoid Short Acting Opiates for 24 hours to minimize chances of precipitated withdrawal.

Heroin
Crushed OxyContin®
Percocet®
Vicodin®
Oxycodone 

Please verify all information with your doctor every situation is different and drug interactions change things.

VERY IMPORTANT — Avoid Long Acting Opiates for 24 hours to minimize chances of precipitated withdrawal.

OxyContin® (Orally)
Methadone * really long lasting get medical attention first!

* It is recommended that patients transitioning from methadone to Buprenorphine slowly taper down on the methadone, for at
least one week. Last dose must be no less than 36 hours prior to induction, and better if be 96 hours or more.  Expect discomfort
for a few days coming from Methadone.
 

Does Suboxone Work?  Is it worth the risk?

I think that Suboxone is a wonderful medication that probably saved many lives including one of my friends.  So yes, it works and works well.  My recommendation is to find a doctor that believes in a shorter duration of treatment with Suboxone.  Longer periods of time on Suboxone will end up being difficult to wean down below 1mg so you’ll need to go below 1mg in slow, very slow micro amounts.  You can cut an 8mg strip into at least 24 tiny squares giving you around .3mg dose which believe it or not is enough to remove morning withdrawal or mild withdrawal discomfort, but it takes an hour or two.   Recognizing Suboxone’s strength is important, don’t go from one addiction to another.

Good luck and stay clear of Precipitated Withdrawal!

Another article about Precipitated Withdrawal
 
Sources of information:
Center for Substance Abuse Treatment.
FDA & Suboxone®/Subutex® www.suboxone.com/pdfs/DosingGuides.pdf
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Mar 04

Suboxone Precipitated Withdrawal – In Simple Terms

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Precipitated withdrawal and blockade effect

Precipitated Withdrawal of SuboxoneWe have all heard about the feared “precipitated withdrawal“, or heard some horror story about it.  What is the precipitated withdrawal or “precipitated withdrawal syndrome.”?   The dangerous part about it, is that it does not occur in all persons tolerant to full-agonist opioids, but rather depends on the severity of addiction and time elapsed from their last dose.  This can lead to a false sense of security or bad information shared from one persons’ experience.  Though this writer has not witnessed a single person who has suffered precipitated withdrawal, I have received letters from people who have, and I suggest that everyone respect this possibility.  Check out the Suboxone Tapering Chart where you can build your own plan to taper off of Suboxone so slowly that you won’t feel any pain at all!

Precipitated Withdrawal – In Simple Terms

Suboxone Withdrawal Precipitated WithdrawalBuprenorphine (Subutex) itself binds more strongly to receptors in the brain than do other opioids, making it more difficult for opioids (or opiates) to react when buprenorphine is in the system.  When one takes opiates to get “high” the bupenorphine is already bound to the opiate receptors letting the opiates go to waste and causing the addict to not get “high”, or not get “high” like he/she was used to.   Buprenorphine has a very long half-life, meaning it stays active in your body for a long time and even if you stop taking it on Thursday with the intention of getting high on Saturday, well, it just isn’t going to work.  A person on a Suboxone therapy will have relatively high-levels of buprenorphine in the system and it would take weeks before the receptors become available for opiates to bind, and allow the user to get “high”.  May Suboxone users who try to get high end up wasting money chasing a high that they will not be able to attain.

Blockade effect – Is it the same as precipitated withdrawal?

In simple terms, the blockade effect is what causes the precipitated withdrawal.  Buprenorphine the active ingredient in Suboxone binds very strongly to receptors in the brain than do other opoids.  So it is that blockade effect that may cause precipitated withdrawal syndrome.

A person is suggested to wait until withdrawal symptoms start before starting Suboxone.  In reality users report switching back and forth between Suboxone and Opiates without apparent problems but this is dependent on person, dose, length of time addicted, and cross-tolerance.

Precipitated Withdrawal causes memory loss?

The blockade effect of Suboxone also has the result of blocking endogenous endorphins from binding to receptors thus causing blockade in the reward system.  This has been shown to cause mood alterations, and alterations in memory, particularly deficiencies of mental capacity.

Switching from Methadone to Suboxone – Not Easy

Switching to Suboxone from methadone is usually difficult especially when Methadone doses were higher than 30 mg/day.  The 30mg dose is low for Methadone and most find it difficult to reach.   Those that perform a slow taper have the best success at dropping to a low-enough dose of Methadone to switch to Suboxone.

Users of oxycodone (Roxy’s Oxy’s Blueberries, Berries, Blues, or even common opiates, need to wait a maximum of only twenty-four hours before they are fully in withdrawal and ready to begin Suboxone.

Naloxone is NOT what causes precipitated withdrawal

It is common belief the naloxone causes the precipitated withdrawal, but in reality it prevents one from abusing the Suboxone by intravenous route.  Buprenorphine alone is responsible for precipitated withdrawal, or the blockade effect because of it’s very high binding affinity with opiate receptors.   Because of this false belief demand for buprenorphine without naloxone is high among addicts.

Precipitated Withdrawal – Fact or Fiction?

It is this authors’ personal belief that twenty-four hours recommended between opiates and Suboxone is rarely followed and switching from weekend opiate binges to Suboxone only 8 -12 hours later has been reported by some addicts.  This author has received comments from readers warning about precipitated withdrawal, and heard horror stories so this author believes one should follow doctors orders exactly to be safe.

How to successfully wean from Suboxone

Suboxone Taper Chart - Opiate Withdrawal Minimization

The Subotex Exclusive - Suboxone Taper Charting Software!

My personal experience with Suboxone was a positive one, after a couple failures.  I was able to taper off of Suboxone without any significant problems.  The key was realizing that even a 1mg dose of Suboxone is very powerful.  One must taper extremely slowly down to below 1mg daily, and eventually to as small a dose as one can make using the strips– so that one strip will last about two weeks.  When Suboxone users realize (and doctors believe) that one fourth of a 1mg dose works just fine at removing withdrawal symptoms after several month off opiates they will be able to taper off.  Again, it is my strong belief that unless one respects the sheer power of Suboxone they will be forever hostage to it.

My advice to anyone struggling getting off Suboxone.  Realize that 8mg, 16mg, 24mg are necessary at first, but after a few weeks and one is stable, one can rapidly decrease to down around 1mg daily at which time they will find stopping difficult.  A 1mg dose after being on Suboxone for a few weeks is in my opinion just as effective as an 16mg dose during the beginning of the treatment.  Once you are down to 1mg, you should plan on taking two more months taking sub-1mg doses (this means cutting a strip into more than 8 pieces, preferably 16 pieces) and only take the dose when you feel “bad”.  If you take a dose after feeling “bad”, know in your mind this stuff is very powerful, you only need to taste the “orange” for 10 seconds or so.  Then wait at least an hour before thinking the dose didn’t work and taking another.  Small doses work, but they do take some patience.  If you can make a strip last two weeks THEN you can think about stopping without much pain.  Suboxone doctors would laugh at this last paragraph, but this author has witnessed several people learn this the hard way.

I would love to hear comments from others!

Peace out!

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Jul 10

Suboxone Precipitated Withdrawal – Fact or Fiction?

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Have you heard about precipitated withdrawal caused by Suboxone, but not heard of any actual cases of it?

Suboxone Withdrawal Precipitated WithdrawalI’ve seen my share of friends and friends of friends go from Suboxone treatment to falling off the wagon, back to Suboxone treatment over-and-over again while not experiencing the so-called precipitated withdrawal.  I’m sure that it must really be a valid concern but I wonder if the risk is much lower than we are lead to believe.  If you know anyone who has experienced precipitated withdrawal from Suboxone please leave a comment and let us know.  I know of people who have gone from blue to orange the same day and not experienced the so-called precipitated withdrawal.   You should never try taking Suboxone without doctor supervision, and if your doctor has you take Suboxone too close to coming off other opiates such as oxycodone (Roxies, Blues, Blue-Berries, Berries, 30′s) you should remind your doctor about precipitated withdrawal.

What is Suboxone induced precipitated withdrawal?

Suboxone Withdrawal Precipitated WithdrawalIt is a rapid and intense onset of opiate withdrawal symptoms precipitated by taking Suboxone shortly after taking high doses of opiates, specifically while not in full withdrawal.  The simple explanation of why it happens is that Buprenorphine (in Suboxone) has a higher affinity to your opiate receptors than opiates themselves so if you are not feeling withdrawal the Suboxone basically clears off what opiates are bound to your receptors and replaces the opiate with Buprenorphine.  This rapid removal of opiates is supposedly what triggers the precipitated withdrawal.

For more information about the Suboxone precipitated withdrawal you can visit The National Alliance of Advocates for Buprenorphine Treatment, yes believe it or not,  there is an organization dedicated to Buprenorphine treatment!  The organization also has a link to a scale used for measuring your level of withdrawal you are experiencing.

Your Opiate Withdrawal was How Bad?

Take a look at the Clinical Opiate Withdrawal Scale (COWS) over on the National Alliance of Advocates for Buprenorphine Treatment site and you can get an objective idea of how bad it really is.  Tell us about how bad yours was by leaving a comment!   Keep it honest, no fishing stories here. lol

Addicted, dependent?  Find out if you are you dependent on opiates or not?

The Suboxone official website has a link to a questionnaire for testing whether you are dependent or not.   I don’t know much about the subject myself.

 

Tapering Off of Suboxone?    Try the Suboxone Taper Charting Software.

Suboxone Taper Chart - Opiate Withdrawal MinimizationTake a look at version 2 of our Suboxone blood plasma half-life elimination tool.

This do-it-yourself tapering chart can help give you a visual on how the drug is eliminated from your system and might help your doctor in determining a pain-free and smooth taper plan.   This sample plan is a 60 day taper starting at 16mg of Suboxone and ending with 1mg spaced out every third day.  Here is a link to the Suboxone taper planning tool, remember it is for entertainment purposes only and you should never adjust your medication dosages without discussing with your doctor.

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