Category Archive: Recovery

Sep 04

Florida Sunset from Webster, Florida

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This post doesn’t really fit the blog category but I really liked the sunset a lot and thought it was peaceful to look at. Hope you agree. This was taken near Webster, Florida in August of 2014 around 8:30 p.m. (est.) I put the picture under “Recovery” and “Support” because it could help with both!

 

Sunset

Sunset in Webster, Florida

Permanent link to this article: http://www.subotex.com/florida-sunset-webster-florida/

Jul 25

Buprenex, Buprenorphine Started As Schedule V Narcotic in USA, 1985

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Buprenorphine Drug Scheduling Timeline

Buprenorphine was first marketed in America in 1985, it was then scheduled by the FDA as a Schedule V narcotic. The only available product in the United States at that time was a very low-dose formulation intended for injection.

It was sold under the brand name Buprenex®. The FDA said that diversion, abuse & trafficking was occurring in Europe and other parts of the world. Considering the strength of Buprenorphine, it doesn’t surprise me that it was misused and/or trafficked.

Anyone who has attempted to stop taking Buprenorphine (aka Suboxone) knows how difficult it can be, sometimes more difficult than quitting other addictive opiates. If you are trying to taper from an addictive opiate or suboxone, you can check out the suboxone taper calculator on this site, or check out the new one on http://warm-turkey.com/HalfLife

DEA Scheduling of Buprenophine

 

Subutex and Suboxone were approved by the FDA in 2002 as schedule III Narcotic

The Food and Drug Administration (FDA) approved two buprenorphine products (Suboxone® and Subutex®) for the treatment of opioid addiction.

 

Both products are high dose (2 mg and 8 mg) sublingual (under the
tongue) tablets:

  • Subutex® is a single entity buprenorphine product
  • Suboxone® is a combination product with buprenorphine and naloxone in a 4:1 ratio, respectively.

 

DEA Places Burprenorphine Products In Schedule III in 2002

The DEA placed buprenorphine and all products containing buprenorphine into schedule III in 2002. Since 2003, diversion, trafficking and abuse of buprenorphine have become more common in the United States.

 

FDA Approves Extended Release Buprenorphine Product - Butrans® in 2010

In June 2010, FDA approved an extended release transdermal film containing buprenorphine (Butrans®) for the management of moderate to severe chronic pain in patients requiring a continuous, around-the-clock opioid analgesic for an extended period of time.

 

 

Permanent link to this article: http://www.subotex.com/buprenex-buprenorphine-started-schedule-v-narcotic-usa-1985/

Jun 25

Zubsolv Takes On Suboxone In Two Phase 3 Clinical Trials, And The Winner Is . . .

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Zubsolv Phase 3 Clinical Trials – Positive Top-line Results Released

Uppsala, Sweden – June 23, 2014 Orexo AB (publ) announces the results of two clinical trials assessing Zubsolv for induction of Buprenorphine maintenance therapy in patients with opioid dependence.

Nikolaj Sorensen, Chief Executive Officer of Orexo, noted “We know a main barrier for DATA2000 certified physicians to start treating opioid dependent patients, is perceived difficulties in the initiation phase of treatment. With an expanded label Orexo can take an active role to encourage and educate the certified, but not active, prescribers in initiation of treatment and improve access to treatment for patients suffering from opioid dependence”

A total of 1,068 opioid dependent patients, showed that over 90% of patients treated with Zubsolv were retained in treatment at Day 3 using a 30% . (emphasis added by author, this is impressive)

The full press-release for the clinical trials are here.

Zubsolv & Suboxone are chemically similar containing buprenorphine & naloxone

 

Zubsolv 5.7 mg Sublingual Tablet

Zubsolv 5.7mg

suboxone241

Suboxone 8mg

Zubsolv is the newest drug available for treatment of Opioid Dependence. The current leader-on-the-block for treatment of Opioid Dependence is Suboxone. Suboxone has been around for several years and is chemically similar to Zubsolv in that both medications consist of two drugs Buprenorphine and Naloxone.

 

What is Buprenorphine?

Buprenorphine is a narcotic analgesic, and it decreases pain by working in the brain and nervous system. Put simply, it is a habit-forming narcotic pain-killer in the same ballpark as other narcotic pain-killers such as Oxycodone or Hydrocodone. All narcotic pain-killers are capable of causing addiction problems and are likely to cause dependence problems with extended use.

What is Naloxone?

Naloxone prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Naloxone is an essentially pure opioid antagonist, i.e., it does not possess the “agonistic” or morphine-like properties characteristic of other opioid antagonists. When administered in usual doses and in the absence of opioids or agonistic effects of other opioid antagonists, it exhibits essentially no pharmacologic activity.

Why do Zubsolv & Suboxone contain Buprenorphine & Naloxone?

The combination of buprenorphine and naloxone is what makes Zubsolv & Suboxone effective at treating opioid dependence. The buprenorphine alone would be like taking any other narcotic pain-medicine, however when mixed with Naloxone it makes abuse of the drug difficult if not impossible. The Naloxone displaces opiates so it prevents a dependent user from abusing the drug and getting intoxicated in a way that would lead to addiction. The Naloxone also makes using the drug in IV form not desirable. So the buprenorphine helps to remove the effects of withdrawal while the naloxone keeps the user honest and removes the ability to abuse the drug or use it in a way to get high.

I am generalizing here, but in my understanding this is the basic concept.

My Personal Experience With Zubsolv Compared To Suboxone

The results of the studies surprised me because I had an opportunity to try Zubsolv and it was my opinion that the Zubsolv 5.7mg was much less effective than the Suboxone 8mg strips. After making my opinion about Zubsolv I decided to share it via a Twitter post. I didn’t hold anything back when sharing my opinion, as you can see in the Tweet below.

First Tweet About Zubsolv:

 

I received a very polite response from Chris, he believed that my experience was likely due to the placebo effect and I pretty much discounted that theory immediately because my experience seemed real. When the same Twitter user replied again five days later, he informed me of a clinical study that was completed and was about to be released.

I am aware that placebo-effect is very real, and in light of the study I was willing to entertain the theory that my “mind mighthave been playing tricks on me”, but I was still pretty sure that I was right.

Responses from Twitter user @Christipojk

 

Bigger is always better, right?

After reading the full press release and results of the studies, it is my belief that placebo-effect really did cause me to believe Zubsolv was less effective than Suboxone and I suspect this will be common among other Suboxone loyalists. It is easy to fall for this belief considering that Zubsolv is a smaller dose, and in most peoples’ mind a smaller dose will not be as good as a larger one.

I am used to making one Suboxone 8mg strip last about a week by slicing it into eight equal parts, but when Suboxone wasn’t available and I had the opportunity to try Zubsolv I burned through 5.7mg tablets at the rate of one every three to four days– which was depressing as the medication is relatively expensive.

Micro-Doses of Zubsolv Are Challenging Considering The Small Tablet Size

Zubsolv 5.7 mg Sublingual Tablet

Zubsolv 5.7mg

 

Part of the problem with micro-doses of Zubsolv may be the difficulty in cutting the small Zubsolv tablets into small doses. Cutting a 5.7mg Zubsolv tablet (very small in size) into seven equal parts is close to impossible as the tablets are tiny and they crumble easily when you try to cut them. This alone may make Suboxone strips a better choice for some people. 

 

Suboxone 8mg strips on the other-hand are very easily cut into eight, or even sixteen even parts using a razor blade or sharp scissors.

About Zubsolv®Zubsolv (buprenorphine and naloxone) sublingual tablet (CIII) is indicated for the maintenance treatment of opioid dependence and should be used as part of a comprehensive treatment plan, which includes counseling and psychosocial support. Treatment should be initiated under the direction of physicians who are certified under the Drug Addiction Treatment Act of 2000, and who have been assigned a unique identification number (“X” number).
Zubsolv sublingual tablets can be abused in a manner similar to other opioids, legal or illicit. Clinical monitoring appropriate to the patient’s level of stability is essential. Liver function tests should be monitored before and during treatment. Children who take Zubsolv sublingual tablets can have severe, possibly fatal, respiratory depression. Emergency medical care is critical. Keep Zubsolv sublingual tablets out of the sight and reach of children.

Permanent link to this article: http://www.subotex.com/zubsolv-vs-suboxone-clinical-trial/

Jun 25

Suboxone $50 Copay Card – Save Money on Suboxone For 2014

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Suboxone $75 Copay Card

Suboxone Savings Card 2014

I wanted to let everyone know that Suboxone is offering a $50 Copay Card again this year, it is good until the END of 2014!  If you are taking Zubsolv, there is a similar program to save you money. The Zubsolv Savings Card for 2014.

Details of the Save on SUBOXONE Film Program

  • Save every month on SUBOXONE film
  • If you use insurance, save up to $50 each month (typically means zero copay for privately insured patients)
  • If you are not using insurance, save $50 each month on 2mg or 8mg prescriptions.
  • If you are not using insurance, save MORE than $50 each month on 4mg or 12 mg prescriptions

Offers are applied at the pharmacy where you get your Suboxone filled.

Print Suboxone Savings Card Now

Print Suboxone Savings Card Now

How Do You Take Advantage Of This Save On Suboxone Deal for 2014?

  1. Ask your doctor to write a prescription for Suboxone film.
  2. Print the savings card. Bring the card to your pharmacy when filling Suboxone
  3. Save through 12/31/2014 (limit one prescriptions per month)

 

Permanent link to this article: http://www.subotex.com/suboxone-50-copay-card-save-money-suboxone-2014/

Jun 25

Zubsolv – RISE Program with free $75 Copay Card

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What is the Zubsolv RISE program?

Resolv to take control of your recovery.  RISE is a 24/7 Support Program offers a selection of online tools and resources to help you build the plan you feel is most helpful to your recovery. The program was developed with the help of people with opioid dependence, and to meet the needs of you.

FREE $75 Copay Card for 2014

Zubsolv Card

Zubsolv Card

RISE—a 24/7 support program

Offering you continuous access to information and resources throughout the recovery process and provides care and support beyond the doctor’s office.

Allows you to get support in the privacy of your own home, to supplement your support at the doctor’s office.

Learn MORE about the RISE program

 

The Resolv to Recover Kit Includes:

  • A FREE $75 Copay Card for ZUBSOLV (2014)
  • Evolv, Resolv, ZUBSOLV: What you need to know, an educational brochure for you and your loved ones
  • RISE: Recovery your way – Highlights the features of RISE and provides you with your RISE enrollment code
  • Demonstration placebo tablets
  • Full Prescribing Information and medication guide for ZUBSOLV
Resolv To Recover Kit

Resolv To Recover Kit

 

Permanent link to this article: http://www.subotex.com/zubsolv-rise-75-copay-card-rise-to-recover-kit/

Jun 25

Zubsolv Savings Card For $75 Valid For 2014

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The Zubsolv Savings Card –  $75 Savings Card For 2014

http://www.zubsolv.com/about-zubsolv/patient-savings.php

Zubsolv Card

Zubsolv Card

I wanted to let everyone know that Zubsolv currently has a program that will save you $75 on Zubsolv scripts via a savings card that you can use at most pharmacies.

PRINT a Copay Card for ZUBSOLV

Orexo / Zubsolv Helps You Save on Your Prescription For Zubsolv

 

  • Orexo, the maker of ZUBSOLV, is committed to helping you access the treatment you need
  • If you’re eligible, this copay card for ZUBSOLV can help lower your out-of-pocket costs like copayments, coinsurance, or deductibles on your prescription for ZUBSOLV. The copay card for ZUBSOLV covers up to $75 of your prescription costs
  • Call toll free 1-888-ZUBSOLV (1-888-982-7658) to see if you are eligible for a copay card for ZUBSOLV
Zubsolv 5.7 mg Sublingual Tablet

Zubsolv 5.7 mg Sublingual Tablet

Zubsolv 1.4 mg Sublingual Tablet

Zubsolv 1.4 mg Sublingual Tablet

Permanent link to this article: http://www.subotex.com/zubsolv-savings-card-75-2014/

May 13

Zubsolv, A New Suboxone Alternative for Opiate Addiction Treatment

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Zubsolv, A New Formulation of Buprenorphine and Naloxone

Zubsolv is a new drug formulation of Buprenorphine and Naloxone. Zubsolv is similar to Suboxone and has been approved by the FDA for the same use, opiate addiction.

  • ZUBSOLV is available in 2 doses for Opioid Dependence, 5.7 mg and 1.4 mg.
  • ZUBSOLV is Individually sealed in the highest level of child-resistant unit-dose blister packs (F1 child-resistant)

Zubsolv v.s. Suboxone for Opiate Dependence

Zubsolv comes in two dose sizes that compete directly with Suboxone’s 8mg/2mg and 4mg/1mg strips and sublingual tablets. Orexo, the maker of Zubsolv claims that the dose formulations are comparable to Suboxone even though they contain lower amounts of Buprenorphine and Naloxone. The lower dose sizes are equivalent because the new drug formulation has a higher bio-availability, meaning that a higher percentage of the dose is available to the human body in this new formulation.

The jury is still out on whether Zubsolv works as well as Suboxone. It is the authors’ opinion that Suboxone and Zubsolv should be compared by their dose size and not the claimed bio-availability of the drug. If I had the choice of Suboxone 8mg/2mg v.s. Zubsolv 5.7mg dose I would take Suboxone as it contains more of the medication.

Dosing Comparison For Treatment of Opiate Addiction

Zubsolv 5.7 mg Sublingual Tablet

Zubsolv 5.7 mg Sublingual Tablet

Zubsolv’s 5.7 mg Burprenorphine with 1.4 mg Naloxone comes in a round Menthol flavored sublingual tablet, and is said to have a higher bio-availability than Suboxone strips making it equally as effective as Suboxone in the 8mg/2mg size.

 

 

 

 

Zubsolv 1.4 mg Sublingual Tablet

Zubsolv 1.4 mg Sublingual Tablet

Zubsolv’s 1.4 mg Burprenorphine with .36 mg Naloxone comes in a triangular Menthol flavored sublingual tablet, and is said to have a higher bio-availability than Suboxone strips making it equally as effective as Suboxone in the 2mg/.5mg size.

 

 

 

 

How to take Zubsolv for Opiate Addiction

Taking Zubsolv is similar to taking Suboxone sublingual film, or sublingual tablets. Simply open the package and place the dose under your tongue allowing it to dissolve naturally. Like Suboxone, movement, talking, or drinking while dissolving the tablet is not recommended. Full instructions for taking Zubsolv can be found on Orexo’s Zubsolv website.

 

Permanent link to this article: http://www.subotex.com/zubsolv-a-suboxone-alternative-for-opioid-dependence-and-addiction/

Feb 02

Suboxone Withdrawal is TERRIBLE – Quitting Suboxone IS Possible

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Freedom from Suboxone Addiction begins as an idea

 

Have you tried to quit Suboxone and felt like you’re never going to succeed?

Beating Suboxone AddictionYou know quitting is the right answer. But quitting is hard. Quitting an addictive drug is like swimming out to sea against the incoming waves. You end up back where you started, over, and over again. Does this sound familiar?

I know that gut wrenching feeling of ending up in the same place. I’m in pain. I’m exhausted. I’m losing hope that I’ll ever make it. Have you ever lost faith?

You are not alone. I was where you are now. I learned how to break free from my addiction. I know that you can too. Are you willing to make one small change?

Suboxone is very addictive and can cause unpleasant withdrawal symptoms. Quitting Suboxone is impossible without making a decision to change.

You made it this far. You can end your addiction. All you need to do is initiate change no matter how small. You can make small changes right?

Congratulations you are on the road to recovery from Suboxone Addiction.

 

The next step in beating Suboxone Addiction is deciding on a change

 

A nuclear submarine is on collision course with a massive iceberg. The course must be changed to avoid catastrophe. Are you ready to change your heading towards a better future?

The captain of the submarine knows his direction of travel must be changed immediately. Without change the sub will crash into the iceberg. It would be a tragedy of epic proportions. Each moment of delay makes the turn away more difficult or impossible. Now is a great time to change direction, don’t you agree?

We can change our destination with a thought. That sounds weird but it is true. The moment you change direction,  no matter how small, you have changed your destination.

It happens instantly why not give it a shot?

Imagine your self-confidence soaring as your small changes accumulate becoming noticeable changes, and you begin to feel better. You will start thinking clearly again. This is how I beat addiction. It’s how you can beat addiction too if you want to.

Now is the time to turn the ship.

Now is the time to begin the change.

Now is the time to alter the destination!

Thankfully, the submarine crew followed orders and it was a happy ending.

Change is the key idea that starts the recovery. The laws of physics are clear that an object in motion is likely to stay in motion. You must make change a top-priority. If you accomplish only one thing today, decide what change you are willing to make to beat Suboxone addiction.

Are you ready to end the Suboxone addiction once and for all?

 

The most important step is making the change that you decided on

You need to make your change and make it permanent. After you make your change then you should repeat the process from the beginning but make each change more difficult. It may take several months to quit Suboxone and avoid withdrawal symptoms. If you haven’t seen my Suboxone Taper Charting tool you may want to work with your doctor and plan a very gradual taper plan.

Addicts are brilliant people. It is proven that addicts tend to have higher IQ’s than non-addicts. Then why isn’t beating an addiction easier?

I wish that I had an answer to the question.

I do have a solution to the problem. You can conquer your addiction starting today. You simply need the right motivation. You need to want the change before you can make it happen.

Have you decided what change you want to make today?

Knowledge acquisition IS change

You can start by learning about addiction.

Learning about addiction will help you to conquer it. The submarine captain has studied the enemy so the enemy can be destroyed. Knowing the enemy helps defeat the enemy. Addiction is the enemy, right?

It doesn’t matter how small your change is. The smaller your change the better chances of success! What changes can you commit to right now?


A drug holiday IS change

You can initiate drug holidays or times when you will NOT use the drug. It doesn’t matter how small the window of time is as long as you are serious about sticking to it. Don’t make your change too difficult and set yourself up for failure.

Refuse to use on Sunday.

Refuse to use between 9am and noon.

Refuse to use on holidays.

These are only ideas. What small change will you make today?

Write it down somewhere where you’ll see it every day. If you can’t do that than do something to symbolize the decision like tying a string on your finger. Hold yourself accountable to the small change. I know this probably sounds corny, but it’s serious. Make your changes SMALL so you easily handle them. I mean really small too, so that you could bet your life being able to do it. OK?

Small change is easier than big change.

Small change has the highest probability of succeeding. If you make a small change in the right direction your confidence will soar. This pattern of small, steady changes will take you to a place you never thought existed without drugs.

I learned how to escape addiction with the help of others. My present, and future is bright and hopeful. I know you will succeed because you are still reading. Will you stick with me?

You are almost there. The next step is urgency.

 

Recovery from Suboxone addiction works best with a sense of urgency

 

Urgency is driven by fear or passion.

Change is critical in quitting SuboxoneIf you don’t have fear or passion than you don’t have urgency and you are unlikely to change course. Urgency means making change your first priority. Can you think of a change that might be good for you?

If you don’t make changes than you will never change the destination. You will end up at the same place over, and over again. Your life will not get any easier until you start to make changes. Every day, every week that goes by makes it more difficult to quit. You know in the back of your mind that something needs to change. Are you with me?

Could you NOT use for the first ten minutes of each hour?

You could easily not use from the top of each hour until ten minutes after the hour. I mean, ten minutes can not be that hard. Sure, it might be uncomfortable if you are partying and you suddenly stop for a break. Your partying friends will laugh but they’ll watch and expect you to fail. Do this every day, every week, and you will begin glowing with confidence. Your confidence will become contagious. Can you see it?

Are you not ready to reduce usage yet? No problem.

You can still begin to change now.

Learning about addiction is action. Learning will help you understand the enemy. You can destroy the enemy with knowledge and time. Imagine how you will feel once you have conquered addiction. Make knowledge your first change.

Find a good book about addiction so you can learn.

If you don’t do it now while the voices aren’t telling you otherwise, you may never do it. Start steering your life in the right direction today. Start your change now with urgency because life is not a drill. You may have dodged bullets until now but you can’t forever. You already know this though, right?

I picked two of my favorite books on addiction and they are both really cheap. You can probably buy both of them for less than it would cost for one Suboxone tablet on the street. It’s hard to believe that one pill costs the same as two books that could save your life. I’m sure you are tired of wasting money on Suboxone, right?

The books I recommend are shown as links within this article. Consider reading your book with a friend. Two people have a better chance of success than one.

It is not heroin or cocaine that makes one an addict, it is the need to escape from a harsh reality. There are more television addicts, more baseball and football addicts, more movie addicts, and certainly more alcohol addicts in this country than there are narcotics addicts. Shirley Chisholm

In the interest of full disclosure, I am an affiliate of Amazon. The prices are exactly the same whether you use an affiliate link or not.

Consistent change, a sense of urgency and time are the pillars of success

Some people don’t have addictive personalities. Some people have strong will-power. We weren’t blessed with will-power but we were blessed with intensity.

Addicts do things with great intensity. Now is the time to get intense and make a small change.

Then another change. And another. You get the picture right?

Now is the time to stay on track and continue changing your destination. Begin making your first change today. And remember that knowledge is a start in the right direction.

I’m excited that you have made it this far.

You are obviously ready to quit Suboxone for good and I’m confident you will succeed.

Its time to crush your Suboxone addiction while there is still time.

Suboxone Withdrawal - How to quit Suboxone once and for all

 

What are your thoughts about this article? I hope it helped motivate you to make a change. I hope it starts the same fire in you that it started for me. I beat Suboxone addiction and so can you.

I would also LOVE to hear any success stories, or lessons learned that I can pass on to others.

 

 

 

Permanent link to this article: http://www.subotex.com/why-are-you-still-addicted-to-suboxone/

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